I would put a lefty anywhere if it contributed to our best lineup. I used to have a lefty SS in travel ball. It will be rare to see a lefty at 2B, SS and 3B in college because by then, the talent level of the players will be close enough that the disadvantages of being left-handed will likely make the righty the better option.
I don't think playing a lefty at 2B, SS or 3B in high school or travel hurts that player for recruiting, though, as any college coach will see the athlete and simply transfer her to the OF in their mind. It probably actually helps them, as the college coach is probably thinking that this girl is a good enough athlete to be placed in the infield, despite being a lefty.
I don't see a lefty at 2B being much of a disadvantage. As someone above said, they are more natural for covering 1B on bunts. You won't get 6-4-3 DPs, but that will cost you maybe one out per season. And they are in a better position to start a 4-6-3 DP. The angle of a throw to 1B on a ground ball is a tad awkward, but not likely to cost a team more than one or maybe two outs per season.