Generally speaking, I'm going to play a more skilled defensive player at 2B vs. 1B. 2B gets a lot more balls actually hit to them than 1B and, in fact, most teams I've been associated with, 2B got more balls hit to them than any other defensive position. You certainly need more range at the 2B position, and have to be prepared to cover either 1B or 2B. With that being said, a highly skilled 1B who can come in to cover the bunt, go back on a pop up, or who can dig a bad throw out of the dirt is worth their weight in gold.